Protein Details: TWiK family of potassium channels protein 9

Protein ID

ICDB_Pro_0868

Protein Name

TWiK family of potassium channels protein 9

Gene Name

twk-9; ZK1251.8

Organism

Caenorhabditis elegans

Length

568 amino acids

AlphaFoldDB

AF-Q23435-F1-model_v4.pdb

Function

Sequence

MKCSFHIPEKYQWASTLFVHVALIAGVAVYTVFGALSMQWLESPDRVRALLKRELKPVESLPPPPSISGLPDRITRVYLGEELAILDPGVHECLERTILTLFHDTKCDPYSFEHLNIELIDRCYAEANVPIPEGYGGQPRKKIKNKEEEKDVIDETPAEKWSIGNSVIFAFTVITTIGYGHVAPETFEGRLFLIFYGVIGVPFTLLTIADLGMFLTRFLKNLLTMARRFAHYLVKLYQKAKKQRNKSQKTSPVMPDSERSEVWNTGKEMKEMSMRTAREPGEGDEIEVIENGNDENGKEEDEEEPENNEPRKTEESIALGITFTCYLVAGAKILSVYEPEMDFFKALYFNFVTLTTIGLGDFVPKSFDYLLITLIYIGIGLALTTMAIEIAADLLKKLHYIGRKMENVGQAVVWFGGKKMTMKSLVKHLGDQFNIPEEELANFDMSAFVDNAIKVEKGEIATLRKPPTPPVVFRERAFSFSNVRNSSESALKYVDDNRFSKTTQPTIYTVIIHETTRTIDTLHNLADAIRRDPSIPRLDLDVHYLTDMSAPTSFDENYLRTYTNARRK

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed in ray A-type neurons and cell bodies. Also seen in head; pharyngeal and phasmid neurons; and in coelomocytes.

DOI ID

10.1126/science.282.5396.2012; 10.1016/j.ydbio.2004.02.020

RefSeq

NP_501724.2